Current Landscape of Genome-Wide Association Studies in Acute Myeloid Leukemia: A Review

Acute myeloid leukemia (AML) is a clonal hematopoietic disease that arises from chromosomal and genetic aberrations in precursor cells. AML one of the most common types acute adults; however, it relatively rare overall, comprising about 1% all cancers. In last decade or so, numerous genome-wide association studies (GWAS) have been conducted to screen between hundreds thousands millions variants across many human genomes discover polymorphisms associated with particular phenotype. oncology, GWAS has performed almost every commonly occurring cancer. Despite increasing number published regarding other malignancies, there paucity for AML. this review article, we will summarize current status